Can a combination treatment help people newly diagnosed with type 1 diabetes keep making their own insulin longer? Learn more today to see if you or your child may be eligible to participate.
Join us in learning whether a combination treatment may help people produce their own insulin longer and have better control of their blood glucose.
Participants will help researchers learn whether a new treatment can help people with newly diagnosed Type 1 Diabetes (T1D) keep making their own insulin for a longer time, which may help to control blood sugar.
You may be eligible to participate if you →
Have been recently diagnosed with T1D and can start the treatment phase within 6 months of your diagnosis.
Are between 9 and 20 years old.
Weigh more than 66lbs.
Can read and understand English or Spanish.
Use only insulin to control blood sugar (no other glucose-lowering medicines).
What will I do if I am in the study?
Once you enroll you will be in the study for up to 3 years. Over the 3 years there will be around 12 office visits and at least 6 scheduled phone contacts which will include:
- 2 IV infusions of ATG
- Under-the-skin (subcutaneous) injections every other week (adalimumab or placebo) OR taking a daily pill (verapamil or placebo)
- Wear a Continuous Glucose Monitor (CGM)
- Physical Exams
- Electrocardiograms (ECGs) (to check how your heart beats)
- Have blood drawn for lab tests
- Daily Insulin Recording
- Mixed Meal Tolerance Test (MMTT) (to see how well your pancreas makes insulin)
For more information, please visit ClinicalTrials.gov or see the Recruitment Flyer
Please contact a site near you if you are interested in enrolling.
This study is sponsored by City of Hope and coordinated by the Jaeb Center for Health Research. It is generously supported by philanthropic funding including the Wanek Family Project for Type 1 Diabetes at City of Hope
