CURRENT PROJECTS
JDRF ARTIFICIAL PANCREAS PROJECT (APP)
PEDIATRIC DIABETES CONSORTIUM (PDC)
T1D EXCHANGE
- Continuous Glucose Monitoring Intervention in Teens and Young Adults (CITY) – an RCT of CGM use in teens and young adults.
- Strategies to Enhance New CGM Use in Early Childhood (SENCE) – an RCT assessing continuous glucose monitoring alone and combined with a behavioral intervention in youth less than 8 years of age with type 1 diabetes
- Wireless Innovation for Seniors with Diabetes Mellitus (WISDM) – an RCT assessing continuous glucose monitoring in older adults with type 1 diabetes
- Hybrid Closed Loop Insulin Delivery System Data Collection (HYCLO)
NON-NETWORK STUDIES:
- A Pivotal Study of t:slim X2 with Control-IQ Technology (iDCL protocol DCLP3)
- A Pivotal Study of t:slim X2 with Control-IQ Technology – Extension Study (DCLP3X)
- A Study of t:Slim X2 with Control-IQ Technology in Youth with Type 1 Diabetes (iDCL protocol DCLP5)
- An Observational Study of Individuals with Type 1 Diabetes Using the Loop System for Automated Insulin Delivery
- Continuous Glucose Monitoring in T2D Basal Insulin Users (MOBILE)
- Day-and-Night Home Closed-Loop in Young People with Type 1 Diabetes (DAN05)
- PID vs PID + Fuzzy Logic Crossover Study in Adolescents and Young Adults with Type 1 Diabetes (FLAIR)
- A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes (PERL) Continuous Glucose Monitoring Study
- Closed Loop from Onset in type 1 Diabetes (CLOuD)
- The Artificial Pancreas in Very Young Children with T1D (KidsAP02)
- Closing the Loop in Adults with Type 1 Diabetes under Free Living Conditions with Extension to Evaluate Home Use of Closed-Loop Applying Faster Insulin Aspart Versus Standard Insulin Aspart
- Automated insulin Delivery among Pregnant Women with Type 1 Diabetes (AiDAPT)
- Direct to Patient Initiation of CGM in Diabetes
- Type 1 Diabetes Exercise Initiative: The Effect of Exercise on Glycemic Control in Type 1 Diabetes Pilot Study
COMPLETED PROJECTS
DIABETES RESEARCH IN CHILDREN NETWORK (DIRECNET)
- The Accuracy of Continuous Glucose Monitors in Children with Type 1 Diabetes
- A Pilot Study to Assess the Accuracy of Continuous Glucose Monitors in Normal Children
- A Pilot Study to Evaluate the GlucoWatch 2 Biographer in the Management of Type 1 Diabetes in Children
- A Randomized Trial to Assess the Effectiveness of the GlucoWatch Biographer in the Management of Type 1 Diabetes in Children
- The Effect of Exercise on the Development of Hypoglycemia in Children with Type 1 Diabetes
- The Effect of Basal Insulin During Exercise on the Development of Hypoglycemia in Children with Type 1 Diabetes
- A Pilot Study to Evaluate the Navigator Continuous Glucose Sensor in the Management of Type 1 Diabetes in Children
- DirecNet Questionnaires Public Data Set
- Evaluation of Counter-regulatory Hormone Responses during Hypoglycemia and the Accuracy of Continuous Glucose Monitors in Children with T1DM
- A Pilot Study to Evaluate the Safety of Terbutaline in Children with Type 1 Diabetes
- A Randomized Clinical Trial to Assess the Efficacy and Safety of Real-Time Continuous Glucose Monitoring in the Management of Type 1 Diabetes in Young Children (4 to <10 Year Olds)
- A Pilot Study to Assess the Feasibility of Real-Time Continuous Glucose Monitoring in the Management of Infants and Toddlers with Type 1 Diabetes
- Relationship Between Loss of Beta Cell Function and Loss of the Alpha Cell Response to Hypoglycemia Early in Type 1 Diabetes
- Effect of Metabolic Control at Onset of Diabetes on Progression of Type 1 Diabetes
- Cognitive and Neuroanatomical Consequences of Type 1 Diabetes in Young Children
T1D EXCHANGE
- Severe Hypoglycemia in Older Adults with Type 1 Diabetes: A Study to Identify Factors Associated with the Occurrence of Severe Hypoglycemia in Older Adults with T1D
- Metformin Therapy for Overweight Adolescents with T1D: A Randomized Trial of Metformin as Adjunct Therapy for Overweight Adolescents with Type 1 Diabetes
- Efficacy and Safety of Intranasal Glucagon for Treatment of Insulin Induced Hypoglycemia in Adults with Diabetes
- Assessment of Intranasal Glucagon in Children and Adolescents with Type 1 Diabetes
- Residual C-Peptide in Patients with Type 1 Diabetes
- Metformin Therapy for Overweight Adolescents with T1D: Insulin Clamp Ancillary Study for Assessment of Insulin Resistance
- Racial Differences in Mean CGM Glucose in Relation to HbA1c
- A Randomized Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults with Type 1 Diabetes
- Mini-Dose Glucagon for Adults with Type 1 Diabetes: A Study to Assess the Efficacy and Safety of Mini-Dose Glucagon for Treatment of Non-Severe Hypoglycemia in Adults with Type 1 Diabetes
- Beta Cell Function and Glucose Counter-Regulation During the Progression of Type 1 Diabetes
- The Use of Mini-Dose Glucagon to Prevent Exercise-Induced Hypoglycemia in Type 1 Diabetes
- Improving Family Management and Glycemic Control in Youth
- A Study to Assess Continuous Glucose Sensor Profiles in Healthy Non-Diabetic Subjects
NON-NETWORK STUDIES:
- JDRF Continuous Glucose Monitoring (JDRF CGM RCT) – Public Dataset
- In Home Closed Loop Reduction of Nocturnal Hypoglycemia and Daytime Hyperglycemia (IHCL) – datasets available on JDRF Public Website
- The Insulin-Only Bionic Pancreas Bridging Study
- A Randomized Clinical Trial to Assess the Efficacy of Predictive Low Glucose Suspend Versus Sensor-augmented Pump Therapy in the Management of Type 1 Diabetes (PROLOG)
- Continuous Glucose Monitoring in Pregnant Women with Type 1 Diabetes (CONCEPTT) CGM Data Management Center
- A Randomized Trial to Assess the Effect of Continuous Glucose Monitoring on Glycemic Control in Adults with Type 1 Diabetes Using Injections for Insulin Delivery (DIAMOND)
- A Randomized Trial to Assess the Effect of Continuous Glucose Monitoring vs Usual Care in Type 2 Diabetes Patients on Multiple Daily Insulin Injections (DIAMOND)
- A Randomized Trial to Assess the Effect of Initiating an Insulin Pump in Adults with Type 1 Diabetes Using Multiple Daily Insulin Injections and Continuous Glucose Monitoring (DIAMOND)
- A Randomized Clinical Trial to Assess the Efficacy of Adjunctive Closed Loop Control Versus Sensor-Augmented Pump Therapy in the Management of Type 1 Diabetes (iDCL protocol DCLP1)
- Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension: An Outpatient Pilot Feasibility and Efficacy Study (PSO3)
- Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children (PSO4)
- Pump Suspension with Hyperglycemia Minimization Nocturnal Inpatient Safety and Feasibility Study (PHM1)
- Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing (PHM2)
- Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents (PHM3)
- Feasibility Assessment of Prototype Nocturnal Hypoglycemia Reduction System (PSO2)
- Inpatient Evaluation of an Automated Closed-Loop Control-to-Range System (CTR)
- Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use (CTR3)
- Treat-to-Range Controller: Meal Assessment (TTR)
- Closing the loop in children and adolescents with T1D in the home setting (APCam08)
- Home testing of day and night closed loop with pump suspend feature (APCam11)
- The Artificial Pancreas in the Very Young Children with T1D – Pilot Study (KidsAP01)