MAJOR CURRENT PROJECTS

Eye Disorders

Cornea Donor Study (CDS)

Objective: To determine whether donor age and other donor factors are predictors of success and failure of cornea transplants.

Diabetic Retinopathy Clinical Research Network (DRCRNET)

Diabetic Retinopathy Clinical Research Network (DRCRNET)

Objective: Facilitating multicenter clinical research of diabetic retinopathy, diabetic macular edema and associated conditions.

Pediatric Eye Disease Investigator Group (PEDIG)

Pediatric Eye Disease Investigator Group (PEDIG)

Objective: Facilitating multicenter clinical research in strabismus, amblyopia and other eye disorders that affect children.

Type 1 Diabetes

Diabetes Research in Children Network (DIRECNET)

Diabetes Research in Children Network (DIRECNET)

Objective: To investigate strategies designed to reduce the incidence of hypoglycemia and hyperglycemia in children and young adults.

In Home Closed Loop Reduction of Nocturnal Hypoglycemia and Daytime Hyperglycemia

Objective: To evaluate systems for reducing nocturnal hypoglycemia and for reducing hyperglycemia after meals in people with type 1 diabetes in a home setting

JDRF Artificial Pancreas Project

Objective: To develop algorithms for automated computer control of blood glucose in diabetics and evaluate the effectiveness of experimental systems that incorporate those algorithms.

JDRF Continuous Glucose Monitoring

Objective: To evaluate the effectiveness of real-time continuous glucose monitors in the management of type 1 diabetes in children and adults.

Pediatric Diabetes Consortium (PDC)

Pediatric Diabetes Consortium (PDC)

Objective: To improve the care of children with type 1 diabetes by sharing and advocating best care practices resulting from the collection and analysis of treatment outcome data.

Objective: To improve the comprehensive study of type 1 diabetes (T1D) and create new research opportunities by developing a T1D data exchange with three components: a clinical registry, biobank, and web-based patient portal.

PREVIOUS PROJECTS

Multiple Sclerosis

Controlled High Risk AVONEX® Multiple Sclerosis Prevention Study In Ongoing Neurological Surveillance (CHAMPIONS)

Controlled High Risk AVONEX® Multiple Sclerosis Prevention Study In Ongoing Neurological Surveillance (CHAMPIONS)

Objective: To determine long-term course of patients with multiple sclerosis who were treated with Avonex at the onset of their first demyelinating event.

Longitudinal Optic Neuritis Study (LONS)

Longitudinal Optic Neuritis Study (LONS)

Objective: To determine the risk of and associated risk factors for multiple sclerosis following optic neuritis and the visual course following optic neuritis.